October 2024 – New paper! Deep Genetic Substructure within Bonobos, just published in Current Biology! This is a years-long project co-led by Sojung Han* and Cesare de Filippo* where we reveal high levels of genetic substructure in bonobos, with deep divergence times and surprisingly small estimated effective population sizes. Congratulations to Sojung and Cesare for bringing this to the finish line.
See translations to several languages of a summary of the paper in our new Translations page. And UCL news here.
Credit Cesare de Filippo, original picture Martin Surbeck Kokolopori Bonobo Research Project
September 2024 – Harrison Ostridge has graduated. Congratulations Dr Ostridge!! His thesis and public viva (back in July) were both excellent.
July 2024 – Another summer, another great SMBE meeting. This time in Mexico, where Aida gave a keynote talk on Local Genetic Adaptation in Humans and Other Primates.
July 2024 – Another preprint, Local genetic adaptation to habitat in wild chimpanzees, phenomenal effort with the PanAf consortium, led in our group by
June 2024 – Our preprint Deep Genetic Substructure within Bonobos, by Sojung Han*, Cesare de Filippo* and others has just appeared on the bioRxiv.
May 2024 – Harrison Ostridge has defended his PhD thesis Local Genetic Adaptation in Chimpanzees, with only minor revisions.
March 2024 – Jasmin Rees’s paper Ancient Loss of Catalytic Selenocysteine Spurred Convergent Adaptation in a Mammalian Oxidoreductase has been published in GBE.
January 2024 – Our paper Signatures of Balancing Selection in the Human Genome, Bitarello et al., GBE 2018, has been selected for GBE’s virtual issue of influential papers on inferential methods published in the journal, published to celebrate the 40th anniversary of the birth of MBE.
December 2023 – Alfie Gleeson has graduated from his PhD on The genetic and morphological evolution of facial morphology, congratulations Dr Gleeson!
September 2023 – After graduating, Dr Jasmin Rees gave a fantastic “public viva” talk of her PhD work The role of micronutrients in genetic adaptation to the department. Congratulations on your graduation and on a brilliant talk Jas!!
September 2023 – Our paper on human genetic adaptation to cold ambient temperature is among the top 10% most viewed papers in PLoS Genetics in 2022 and in the PLoS Genetics Top 10% collection of most cited papers.
July 2023 – Really fun first in-person SMBE meeting in years in Ferrara, Italy. Many group members presented their work as talks or posters. See Harrison’s talk on a proper Italian theatre…
February 2023 – Ghost admixture in eastern gorillas by Harvi Pawar, part of her PhD work with Martin Kuhlwilm and Tomas Marques-Bonet, now published in Nature Ecology and Evolution.
May 2023 – Dean Cornish has graduated for his MPhil! His thesis is on Inferences of Local Genetic Adaptation from Palaeolithic Hunter Gatherers. Congratulations Dean!!
March 2023 – Check out our review on Inferring Balancing Selection From Genome-Scale Data, Bitarello et al., just published in GBE with our great collaborators Bárbara Bitarello and Diogo Meyer.
February 2023 – NERC DTP PhD student Finley Glover is joining the group! He will work on the evolution of mito-nuclear interactions in humans and flies with Flo Camus (who is his first supervisor) and us.
February 2023 – The Ghost admixture in eastern gorillas preprint by Harvi Pawar, part of her PhD work with Martin Kuhlwilm and Tomas Marques-Bonet, is on BiorXiv.
January 2023 – Most of us attended the great PopGroup meeting in London, many talks by the group including a keynote by Aida on local adaptation in humans and chimpanzees.
October 2022 – Not news from our group, but exciting. Svante Pääbo, the director of our department when we were in Leipzig, has been awarded the Nobel Prize!! Amazing recognition to his work and to the importance of the fields of human evolutionary genetics and ancient DNA.
October 2022 – Débora Brandt has joined the group. Débora is a a postdoc joining us from Rasmus Nielsen’s lab in Berkeley to study balancing selection in natural populations of Drosophila, with Max Reuter.
September 2022 – The MSci project of Harvi Pawar is now published in PLoS Genetics. Genetic adaptations to SIV across chimpanzee populations. We present evidence of genetic adaptation in chimpanzees to the zoonotic transmission of the Simian Immunodeficiency Virus (SIV), the precursor of HIV. Interesting differences and similarities in the mechanisms of adaptation across time and populations.
Check it out on our publications page.
Twitter feed here.
September 2022 – Two postdocs join the group! Avishikta Chakraborty joins us from Monash University (Australia) and Abhilesh Dhawanjewar from University of Nebraska (USA) to study sexually antagonistic genetic variants in fruit flies using experimental evolution, with Max Reuter.
June 2022 – Aida has recorded a lecture for the general public on the genetics of local adaptation in humans at the Gresham College. Watch it here.
June 2022 – The paper of a long-term collaboration with with Claudia Fontserre and his supervisor Tomas Marques-Bonet, led by Tomas and Mimi Arandjelovic and involving many others, is now out. Population dynamics and genetic connectivity in recent chimpanzee history, where hundreds of chimpanzee non-invasive samples were used by the team to infer the fine-scale demographic history of wild chimpanzees.
May 2022 – New preprint, Genetic adaptations to SIV across chimpanzee populations. Led by Harvinder Pawar, this study analyses full genomes of chimpanzees and identifies very interesting signatures of genetic adaptation to SIV in chimpanzees.
February 2022 – Jasmin and Aida wrote a perspective for Science on a paper that reports the largest genetic genealogy of humans to date.
Check it out on our publications page.
January 2022 – Harrison Ostridge won the first ever Best Twitter Flash Presentation at the 55th Popgroup meeting. Fantastic Twitter Thread, obviously. He was interviewed in the Heredity Podcast too.
Huge congratulations Harrison! UGI, GEE News piece.
December 2021 – We have been awarded two grants to study the population genetics of sexual antagonism in fruit flies, together with Max Reuter. We’ll be hiring several postdocs soon.
November 2021 – David Reher successfully defended his PhD thesis at the Max Planck Institute for Evolutionary Anthropology. We followed the defence online. Amazing work, Dr. Reher!
2020 – 2022 – The four PhD students in the group passed their upgrade during the pandemic. Well done!
2020 – 2022 – There was this pandemic, not sure if you heard about it?
May 2020 – Check out our invited review on The genomics of human local adaptation in Trends in Genetics, led by Jasmin Rees in the group, and with Sergi Castellano at the UCL Institute of Child Health.
March 2020 – New paper on the Identification of Structural Variation in Chimpanzees Using Optical Mapping and Nanopore Sequencin in Genes. Soto et al., led by the group of our long-term collaborator Megan Dennis.
December 2019 – Our paper The impact of genetic adaptation on chimpanzee subspecies differentiation, which revealed likely adaptation to the Simian Immunodeficiency Virus in eastern and central chimpanzees, is published in PLoS Genetics. It was led by postdoc Josh Schmidt (now at the University of Adelaide) and in collaboration with Sergi Castellano at the UCL Institute of Child Health.
UCL news piece.
September 2019 – New paper! Evolutionary and functional impact of common polymorphic inversions in the human genome has been published in Nature Communications. Ginger et al., NatComm (2019).
September 2019 – Sojung Han successfully defended her PhD thesis at the PRBB in Barcelona. Congratulations, Dr. Han!
September 2019 – Our paper on local adaptation of human cold receptor TRPM8, led by former PhD student Felix Key (now at Harvard), has been Highly Recognized by PLoS Genetics: among the three best nominated papers published in the journal in 2018.
UGI,GEE News piece. Announcement.
September 2019 – Congratulations to Derron Abdulla, who defended his project and graduated from his MSc.
July 2019 – Group Alumni Bárbara Bitarello (now at UPenn) receives her award from the Society of Molecular Biology and Evolution for best paper published in GBE by a PhD student, at the SMBE meeting in Manchester.
UGI,GEE News piece.
July 2019 – We welcome Aarthi Seekar (from UC Davis) and María Lucena Pérez (from the Estación Biológica de Doñana), both visiting us for the month of July.
June 2019 – Harvinder Pawar received an award for best presentation, for her talk on her extended MSci project on local adaptation in chimpanzee subspecies. Congratulations Harvi!
June 2019 – Congratulations to Harvinder Pawar and Simran Rai, who just finished their extended MSci project in the group, and graduated.