Hematopoietic stem cell quiescence and DNA replication dynamics maintained by the resilient β-catenin/Hoxa9/Prmt1 axis

Spatial Architecture of Myeloid and T Cells Orchestrates Immune Evasion and Clinical Outcome in Lung Cancer

Versican associates with tumour immune phenotype and limits T cell trafficking via chondroitin sulfate

Drug-resistant EGFR mutations promote lung cancer by stabilizing interfaces in ligand-free kinase-active EGFR oligomers

Metabolic priming by multiple enzyme systems supports glycolysis, HIF1α stabilisation, and human cancer cell survival in early hypoxia

Noncoding mutations drive persistence of a founder preleukemic clone which initiates late relapse in T-ALL

ZAP-70 augments tonic B-cell receptor and CCR7 signaling in IGHV–unmutated chronic lymphocytic leukemia

Nilotinib in KIT-driven advanced melanoma: Results from the phase II single-arm NICAM trial

Apparent RNA bridging between PRC2 and chromatin is an artifact of non-specific chromatin precipitation upon RNA degradation

Protein degradation by human 20S proteasomes elucidates the interplay between peptide hydrolysis and splicing

Deep Learning Enables Spatial Mapping of the Mosaic Microenvironment of Myeloma Bone Marrow Trephine Biopsies

High pretreatment disease burden as a risk factor for infectious complications following CD19 chimeric antigen receptor T-cell therapy for large B-cell lymphoma

New method to reveal proteins that bind to specific RNA regions in living cells described

mRNA therapy corrects a rare liver genetic disease known as argininosuccinic aciduria (ASA) in a mouse model of the disease by replacing the defective urea cycle gene and restore its function

Non-coding mutations drive persistence of a founder pre-leukemic clone which initiates late relapse in T-ALL

PD-1 defines a distinct, functional, tissue-adapted state in Vδ1⁺ T cells with implications for cancer immunotherapy

An oncogenic phenoscape of colonic stem cell polarization

Trellis tree-based analysis reveals stromal regulation of patient-derived organoid drug responses

The role of APOBEC3B in lung tumor evolution and targeted cancer therapy resistance

Impact of MYC and BCL2 double expression on outcomes in Primary CNS Lymphoma: a UK multicenter analysis

Cranial radiotherapy has minimal benefit in children with central nervous system involvement in T-ALL